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Albumin, Urine

Alias Microalbumin, Albumin Creatinine Ratio, Random or 24H Urine Albumin
Laboratory Section Chemistry
Methodology

Immunoturbidimetric & Calculation
Random: MALB (mg/g creatinine) = [Microalbumin (mg/L)] / [Creatinine (mg/dL)/100]
24-Hour: [MALB 24H = MALB x Urine Vol (L)]

Preferred Specimen Urine
Transport Container Urine Cup or 24H Collection Urine Jug
Alternative Specimen / Container  
Minimum Volume 10 mL
Preparation & Collection Instructions Routine midstream urine for random collection or entire urine collection for 24 hours (indicate whether random or 24-hour urine collection)
Handling Instructions Screw tight and label container (make sure no urine sample leak). Place the container in the appropriate biohazard plastic bag with the requisition and take it as soon as possible to the laboratory. For 24-hour collection: Best to refrigerate urine sample during collection but do not freeze. Write starting and ending date and time of collection. Record entire volume (mL) on  the container and requisition at the end of 24 hours. Take the entire collection jug or a well-mixed 10- 50mL aliquot with the requisition to the laboratory as soon as possible. Do not acidify or put any preservative. 
Transport Temperature Ambient (15 – 30 oC)
Specimen Stability Ambient: 1 day
Refrigerated (2 – 8 oC): 7 days
Laboratory Receiving Time

In-patient and ER: Monday to Sunday, 24 Hours
Out-patient: Monday to Friday, 8AM to 4PM

Days & Time Performed

Monday to Sunday, 24 Hours

kRejection Criteria

• Specimen older than stability limits
• Urine with preservatives
• Contaminated or leaking specimen
• Quantity Not Sufficient (QNS)
• Unlabeled or Mislabeled specimen
• No record of volume and date/time of collection

Turn Around Time <In-patient> 8 Hours
<Out-patient> 24 Hours
Reference Range

Random Collection: 0 – 29 mg/g creatinine
24-Hour Collection: 0 – 29 mg/day

Limitations Prozone or hook effect may occur with very elevated microalbumin samples (>6000 mg/L).

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